Historical Product Revenue

Reported Net Sales Revenue by Product ($ in 000’s)

Avastin	Q1	Q2	Q3	Q4	Total
2010	1,586,093	1,596,892	1,594,707		4,777,692
2009	1,345,487	1,295,536	1,439,730	1,514,053	5,594,806
2008	980,715	1,084,930	1,180,427	1,239,382	4,485,454
2007	678,068	746,587	797,013	875,084	3,096,752
2006	439,318	516,052	570,551	592,897	2,118,817

Herceptin	Q1	Q2	Q3	Q4	Total
2010	1,337,732	1,349,512	1,300,934		3,988,178
2009	1,210,268	1,133,993	1,226,435	1,278,626	4,849,323
2008	1,105,426	1,195,215	1,211,982	1,186,806	4,699,428
2007	891,761	949,556	979,602	1,015,033	3,835,952
2006	529,585	659,719	761,099	803,576	2,753,979

Lucentis	Q1	Q2	Q3	Q4	Total
2010	759,965	698,890	745,376		2,204,231
2009	462,103	469,736	555,296	615,212	2,102,347
2008	363,615	393,682	460,167	454,922	1,672,386
2007	224,820	219,579	299,995	322,300	1,066,695
2006	–	–	10,689	157,742	168,431

Xolair	Q1	Q2	Q3	Q4	Total
2010	240,904	225,878	251,055		717,836
2009	184,669	181,086	211,006	219,693	796,454
2008	137,875	169,521	177,179	183,753	668,329
2007	129,172	130,700	144,250	147,754	551,876
2006	95,241	99,354	112,608	118,002	425,204

Raptiva	Q1	Q2	Q3	Q4	Total
2010	–	14,224	–		14,224
2009	62,653	21,526	1,502	–	85,681
2008	55,541	57,601	66,992	65,216	245,349
2007	45,134	47,401	52,914	53,885	199,333
2006	32,672	35,458	39,610	41,353	149,093

Synagis	Q1	Q2	Q3	Q4	Total
2010	–	–	–		–
2009	571,486	623,951	57,271	105,314	1,358,021
2008	542,283	574,207	80,930	141,696	1,339,116
2007	478,388	548,227	53,586	139,736	1,219,936
2006	472,362	489,634	30,185	124,629	1,116,811

Tysabri	Q1	Q2	Q3	Q4	Total
2010	293,047	287,925	293,664		874,635
2009	221,854	229,993	257,240	285,481	994,569
2008	129,430	163,076	200,783	233,070	726,359
2007	30,468	48,715	71,972	94,521	245,675
2006	–	–	–	7,890	7,890

Actemra	Q1	Q2	Q3	Q4	Total
2010	52,908	5,405	10,493		68,806
2009	19,504	17,920	30,313	39,888	107,627
2008	1,452	1,377	5,981	12,305	21,116
2007	2,388	873	1,071	1,137	5,470
2006	–	–	–	–	–

Mylotarg	Q1	Q2	Q3	Q4	Total
2010	8,500	8,658	8,142		25,300
2009	8,367	8,406	8,813	8,654	34,240
2008	8,978	8,050	8,225	8,140	33,393
2007	7,879	8,202	8,345	7,878	32,304
2006	8,832	9,084	8,874	16,081	42,871